How to use Hydrozid

Important: Hydrozid should only be used by healthcare professionals

Instructions for use

Hydrozid is as easy as 1-2-3

Step 1

Hydrozid is applied to a lesion directly from the canister. Hydrozid does not require any preparation time; no foam tipped applicators, tubes, replacing spent cartridges.

Step 2

Move the lock extension to the right to open the spray head. Hydrozid is applied to a lesion directly from the canister. No anaesthesia prior to treatment is required.

Step 3

Hydrozid is now ready to use. To avoid damaging the surrounding tissue use one of the application templates provided in the Hydrozid pack. Select the hole matching the size of the individual lesion. Freeze the lesion by applying Hydrozid from a distance of 2 to 3 cm followed by a complete thaw.

After a short interval, repeat the freeze-thaw cycle. Several repeated freeze-thaw cycles are recommended as in a single treatment. The total duration of application to a lesion must be kept within the recommended maximum total (see panel). For large lesions, it is recommended to apply the jet in circular movements from the centre of the lesion toward the edge.

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Recommended treatments

Skin lesion	Recommended Freeze-Thaw Cycle Time	Total Recomende Freeze Time
Verruca plantaris	4x6 to 6x6 seconds	24 to 36 seconds
Verruca vulgaris	4x6 to 6x6 seconds	24 to 36 seconds
Verruca plana	6x3 seconds	18 seconds
Keratosis seborrhoica	2x6 to 3x6 seconds	12 to 18 seconds
Lentigo (facial)	2x3 seconds	6 seconds
Lentigo (non-facial)	2x3 seconds	6 seconds
Acrochordon (skin tag)	2x3 to 2x6 seconds	6 to 12 seconds
Keratosis actinica (facial)	2x4 to 2x5 seconds	8 to 10 seconds
Keratosis actinica (non-facial)	2x4 to 2x5 seconds	8 to 10 seconds
Condyloma	2x6 to 6x6 seconds	12 to 36 seconds
Molluscum contagiosum	2x3 to 2x6 seconds	6 to 12 seconds

Mucosal lesion	Maximum Freeze-Thaw Cycle Time	Total Maximum Freeze Time
Gingival Melanin Hyperpigmentation	6x6 seconds	36 seconds
Cervical Contact Bleeding	6x6 seconds	36 seconds

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Cryotherapy

The term “cryotherapy” comes from the Greek cryo meaning cold, and therapy meaning cure and describes the medical use of freezing to destroy diseased tissue.

Cryotherapy relies upon the fact that different types of skin cell vary in their sensitivity to freezing. Keratinocytes make up 95% of the epidermis and are many times more sensitive to freezing than the network of collagen fibres and fibroblasts in the underlying dermis.

Since warts and other lesions occur in the upper layer of the epidermis, they can be targeted for treatment without causing damage to the underlying tissues.